Phenylpropanoids and polyketides
Medchemexpress LLC Entacapone acid | 160391-70-8 | 98.9% | 250.16 g/mol | C10H6N2O6 | 1MG
Entacapone acid (Tyrphostin AG1290) is a research-grade tyrosine kinase inhibitor (CAS 160391-70-8) used as a biochemical tool to study kinase activity and hepatic protein synthesis. It is supplied as a purified powder with defined storage conditions for stability and long-term use.
- High purity: 98.9%
- Molecular weight: 250.16 g/mol
- Chemical formula: C10H6N2O6
- Reported biological activity: reduces hepatic protein synthesis in vivo
- Available in small research pack sizes, including 1 mg
- Storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month)
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | MFCD00017208 | 99.9% | 208.21 g/mol | C11H12O4 | 10 G
Ferulic acid methyl ester is the methyl ester derivative of ferulic acid used as a research reagent. It shows antioxidant and anti-inflammatory properties, is reported to inhibit p38 MAPK and modulate autophagy, and is suitable for biochemical and cell-based studies; batch-specific purity and safety documentation are available from the manufacturer.
- Methyl ester derivative of ferulic acid with antioxidant activity.
- Reported inhibitor of p38 MAPK and modulator of autophagy pathways.
- Cell membrane and brain permeable, suitable for cell-based assays.
- High batch-specific purity with certificate of analysis and SDS documentation available.
- Available in multiple pack sizes for research use, including a 10 g pack.
Selleck Chemical LLC BLU 451-E1877-25MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Medchemexpress LLC 2-phenylpropionic acid | 492-37-5 | MFCD00002650 | >98.0% | 150.17 g/mol | C9H10O2 | 10 G
2-Phenylpropionic acid (CAS 492-37-5) is an aromatic carboxylic acid used as a research reagent and chemical intermediate in synthetic chemistry and analytical applications. It is commonly supplied reagent-grade for laboratory use.
- High purity: >98%.
- Molecular weight: 150.17 g/mol.
- Chemical formula: C9H10O2.
- Physical properties: melting point ≈5 °C, boiling point 260-262 °C, density 1.1 g/mL.
- Typical uses: synthetic intermediate and analytical reference standard.
- Available in multiple pack sizes suitable for research use.
Medchemexpress LLC 4-hydroxychalcone | 20426-12-4 | MFCD00016488 | 99.3% | 224.25 g/mol | C15H12O2 | 1 ML
4-Hydroxychalcone is a chalcone metabolite supplied as a 10 mM solution in DMSO for research use. It is reported to inhibit TNF-α-induced NF-κB activation and to exhibit anti-angiogenic and anti-inflammatory effects, providing a high-purity, ready-to-use stock for cell-based and biochemical assays. Handle under recommended storage conditions and protect from light.
- 10 mM solution in DMSO.
- High purity: 99.3%.
- Molecular formula C15H12O2; molecular weight 224.25 g/mol.
- CAS number 20426-12-4.
- Inhibits TNF-α-induced NF-κB pathway; anti-angiogenic and anti-inflammatory activity.
- Store protected from light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC 5-methoxyflavone | 42079-78-7 | MFCD00016942 | 100.0% | 252.26 g/mol | C16H12O3 | 50 MG
5-Methoxyflavone is a research-grade flavonoid compound used in biochemical and neuroscience studies. It acts as a DNA polymerase-beta inhibitor and is used in assays probing DNA/RNA synthesis and neuroprotective mechanisms.
- High purity (99.97%) for reproducible experimental results.
- Molecular weight 252.26 g/mol and formula C16H12O3 for accurate compound identification.
- Available in small-scale quantities suitable for screening and assay development.
- Applicable to studies of DNA/RNA synthesis inhibition and neuroprotection.
- Supplied as a white to off-white powder, convenient for handling and formulation.
![Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247989.png-250.jpg)
Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 25 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used in biochemical and cellular research to probe tyrosine kinase-dependent signaling pathways, ICAM1 expression, and TNFα-mediated cytotoxicity. It is supplied as a high-purity research reagent intended for in vitro assays.
- High purity suitable for analytical and cell-based assays.
- Useful for investigating tyrosine kinase signaling pathways.
- Inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Supplied as a stable, solid reagent for easy handling and storage.
- Batch-tested with a certificate of analysis for lot verification.
- Compatible with common solvents for assay formulation.
![Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247968.png-250.jpg)
Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 10 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used in research to block signaling pathways and reduce inflammatory responses, notably by inhibiting ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Potent tyrosine kinase inhibitor.
- Inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Molecular formula C10H5N3O4; molecular weight 231.16 g/mol.
- Purity 98.7% as supplied.
- Soluble ≥125 mg/mL (≈540.75 mM) in DMSO.
- Appearance solid, light yellow to yellow.
- Recommended storage: powder -20°C up to 3 years or 4°C up to 2 years; in solution -80°C up to 6 months or -20°C up to 1 month.
Cayman Chemical Seratrodast 50mg
A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study the roles of the TP receptor in animal airways and in tissue samples
Medchemexpress LLC Chalcone dibromide | 611-91-6 | 95.0% | 368.06 g/mol | C15H12Br2O | 100 MG
Chalcone dibromide is a dibrominated chalcone derivative supplied as a white to off-white solid for research use. It serves as a versatile synthetic building block and bioactive compound in medicinal chemistry and organic synthesis, commonly used to prepare heterocycles and to evaluate biological activity.
- Dibrominated chalcone useful as a synthetic intermediate.
- Solid, white to off-white appearance for easy handling.
- Reported purity of 95.0% for research applications.
- Available in multiple pack formats including 100 mg and DMSO solutions.
- Structural identifiers provided (SMILES) to support characterization.
Medchemexpress LLC 4-methylcinnamic acid | 1866-39-3 | MFCD00002697 | 99.6% | 162.19 | C10H10O2 | 1 ML
4-methylcinnamic acid is a cinnamic acid derivative used in research with reported antifungal activity. It is supplied for in vitro and in vivo studies and is provided as powder or concentrated stock solutions with guidance for formulation and storage.
- Cas number 1866-39-3.
- Molecular formula C10H10O2.
- Molecular weight 162.19 g/mol.
- Purity approximately 99.6%.
- Available as powder and in-solvent preparations.
- Solvent guidance: DMSO for high-concentration stocks.
- Stock preparation guidance for 1, 5, and 10 mM solutions from mg quantities.
- Storage recommendations: powder and in-solution temperature ranges with multi-year stability.
![Medchemexpress LLC (+)-(R)-[(E)-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acryloyl]-2-piperidineethanol | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244110.png-250.jpg)
Medchemexpress LLC (+)-(R)-[(E)-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acryloyl]-2-piperidineethanol | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 50 MG
FK 453 is a non-xanthine adenosine A1 receptor antagonist (compound 1d) used in pharmacological research. It is reported as potent and selective, with an IC50 of 17.2 nM. The compound has chemical formula C23H25N3O2, molecular weight 375.46, and reported purity 99.20%.
- Potent and selective A1 receptor antagonist (IC50 17.2 nM).
- High reported purity suitable for research use (99.2%).
- Chemical formula C23H25N3O2 and molecular weight 375.46.
- Available in small research quantities, for example 50 mg.
- Supplied with supporting analytical data such as COA, HPLC, and LCMS.
Selleck Chemical LLC 3-Hydroxyflavone S4790-25mg
3-Hydroxyflavone (Flavon-3-ol 3-HF 3-Hydroxy-2-phenylchromone) is the simplest molecule of the flavonol class that is usually used in synthesis of biologically active molecules