Phenylpropanoids and polyketides
Medchemexpress LLC Apigenin 7-glucoside | 578-74-5 | 432.38 | 25 MG
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) demonstrates notable anti-proliferative and antioxidant properties, and is effective in scavenging reactive oxygen species (ROS). It is intended for research use only and is not sold to patients.
- Exhibits significant anti-proliferative activity against B16F10 melanoma cells.
- Provokes an increase of subG0/G1, S, and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases.
- Enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.
- Specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibits myeloid differentiation.
- Possesses strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.
Cayman Chemical Apigenin Inhibitors
Inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM; potent inhibitor of NO and PGE2 biosynthesis by reducing iNOS and COX-2 expression
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
Medchemexpress LLC Rutin (trihydrate) | 250249-75-3 | ≥97.0% | 664.56 | 10 G
Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. It has demonstrated excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties, along with cardioprotective and neuroprotective activities.
- Multifunctional natural flavonoid glycoside.
- Demonstrates excellent antioxidant properties.
- Demonstrates excellent anti-inflammatory properties.
- Demonstrates excellent anti-diabetic properties.
- Demonstrates excellent anti-carcinogenic properties.
- Exhibits cardioprotective activities.
- Exhibits neuroprotective activities.
- Decreases acrylamide (ACR)-induced cytotoxicity in PC12 cells.
- May modify cognitive and behavioral symptoms of neurodegenerative diseases by crossing the blood-brain barrier.
Medchemexpress LLC (±)-Catechin | 7295-85-4 | 99.5% | 1 G
(±)-Catechin (rel-Cianidanol) is the racemate of the green tea polyphenol Catechin. Catechin has anticancer activity and induces apoptosis. It has two forms: (+)-Catechin and its enantiomer (-)-Catechin. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM, while (-)-Catechin promotes hBM-MSC adipocyte differentiation.
- Exhibits anti-tumor effects
- Shows anti-obesity and anti-diabetic properties
- Provides anti-cardiovascular and anti-infectious benefits
- Offers hepatoprotective and neuroprotective effects
- Induces adipocyte differentiation
- Increases adiponectin and PPARγ levels
Medchemexpress LLC (-)-Epigallocatechin Gallate | 989-51-5 | >98% | 458.37 | 1 G
(-)-Epigallocatechin Gallate (EGCG) is a major polyphenol found in green tea. It inhibits cell proliferation and induces cell apoptosis, and inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. It possesses potent anticancer, antioxidant, and anti-inflammatory properties against various types of cancers, including colorectal cancer, myeloid leukemia, and thyroid carcinoma.
- Inhibits cell proliferation
- Induces cell apoptosis
- Inhibits glutamate dehydrogenase 1/2 activity
- Possesses anticancer, antioxidant, and anti-inflammatory properties
- Effective against various cancers such as colorectal cancer, myeloid leukemia, and thyroid carcinoma
Medchemexpress LLC Catechin (Standard) | 154-23-4 | 290.27 | 100 MG
Catechin (Standard) is the analytical standard of Catechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- Used as an analytical reference standard.
- Commonly used in qualitative research experiments.
- Commonly used in quantitative research experiments.
- Commonly used in methodological research experiments.
- Suitable for HPLC.
- Suitable for GC.
- Suitable for MS.
Medchemexpress LLC Catechin 7-O-β-D-glucopyranoside | 65597-47-9 | 452.41 | 1 MG
Catechin 7-O-β-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. It demonstrates antioxidant and anti-inflammatory activities, and mitigates mitochondrial dysfunction. This product can be utilized in research pertaining to intestinal inflammatory diseases.
- Exhibits antioxidant and anti-inflammatory activities
- Attenuates mitochondrial dysfunction
- Protective effect against Streptozotocin-induced cell damage
- Mild protective effect against LPS/D-GalN induced lethality in mice
- Prevents intestinal inflammatory damages in rat colitis models
Medchemexpress LLC Rutin trihydrate | 250249-75-3 | ≥97.0% | 664.56 | 50 MG
Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. It has demonstrated excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. It also exhibits cardioprotective and neuroprotective activities.
- Multifunctional natural flavonoid glycoside
- Excellent antioxidant properties
- Anti-inflammatory properties
- Anti-diabetic properties
- Anti-carcinogenic properties
- Cardioprotective activities
- Neuroprotective activities
Apexbio Technology LLC Epigallocatechin 970-74-1 20mg
Epigallocatechin (CAS 970-74-1) is a naturally occurring polyphenolic compound isolated from green tea It is known to modulate multiple cellular pathways including oxidative stress response and signal transduction primarily through its antioxidant properties and its ability to influence enzyme activities and cellular signaling cascades Soluble in methanol and ethanol epigallocatechin can be stored under cool dry and airtight conditions This compound is widely utilized in biomedical research for investigating its potential roles in cellular protection cancer biology metabolic regulation and as a tool for studying redox-mediated cellular processes
Medchemexpress LLC Myricitrin | 17912-87-7 | 99.8% | 464.38 | 25 MG
Myricitrin, a naturally occurring flavonoid, acts as an orally active nitric oxide (NO) and PKC inhibitor. It exhibits central nervous system activity, including anxiolytic-like effects. Myricitrin also possesses antioxidant, anti-inflammatory, antifibrotic, and anti-malarial properties.
- Orally active NO and PKC inhibitor.
- Central nervous system activity (anxiolytic-like action).
- Antioxidant effects (radical scavenger, metal-ion chelator).
- Anti-inflammatory effects.
- Antifibrotic effects.
- Anti-malarial effects (inhibits *Plasmodium falciparum* proliferation).
- Inhibits aldose reductase activity and low-density lipoprotein oxidation.
- Exhibits scavenging activity against DPPH, NO radicals, and H2O2.
- Inhibits TNFα production and enhances RANTES production in LPS-stimulated Raw264.7 cells.